It takes the average reader 18 hours and 42 minutes to read 23 European Symposium on Computer Aided Process Engineering by Yang Yang
Assuming a reading speed of 250 words per minute. Learn more
The impact of upstream and downstream process fluctuations in bioprocesses becomes more pronounced during technology transfer of pilot scale processes into large-scale facilities. Mismatches in equipment sizes upon scale-up combined with process fluctuations can lead to discarding expensive product. Understanding and predicting the root causes of product loss is critical to determining the necessary facility modifications required to meet manufacturing targets. In this work, a decision tree classification method, CART (classification and regression tree), was used to interrogate stochastic Monte Carlo simulation datasets that mimic batch fluctuations in industrial biopharmaceutical batch processes. The resulting binary decision tree not only reveals the impact of process fluctuations on product mass loss but also extracts a series of if-then rules on the critical combinations of factors that lead to unacceptable mass loss levels. The decision tree analysis therefore allows rapid prediction of the likelihood of facility fit issues as well as the batch characteristics that result in product loss.
23 European Symposium on Computer Aided Process Engineering by Yang Yang is 1,088 pages long, and a total of 280,704 words.
This makes it 367% the length of the average book. It also has 343% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 25 hours and 33 minutes to read 23 European Symposium on Computer Aided Process Engineering aloud.
23 European Symposium on Computer Aided Process Engineering is suitable for students ages 12 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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