It takes the average reader 1 hour and 50 minutes to read An Evaluation of Sixteen Combined Anti-HIV 1/2 Screening Assays by Lindsay McAlpine
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The sensitivity and specificity of sixteen current screening assays for the detection of anti HIV-1/HIV-2 in human serum or plasma specimens was assessed against a panel of 357 well characterised serum or plasma specimens. Specimens confirmed to contain anti HIV-1 at typical (n = 64) or low (n = 44) levels of reactivity, specimens containing anti HIV-2 (n = 22), and specimens collected during HIV-1 seroconversion (n = 73) were included to assess sensitivity. Eighty specimens from unselected blood donors and 74 specimens from patients with a range of pathological conditions (including acute viral infections) were employed to assess specificity. Excluding the 73 seroconversion specimens, observed sensitivities ranged from 95.2% to 100%. Observed specificities ranged from 93.7% to 100%. Two of the assays achieved maximum sensitivity and specificity; one of these two assays also gave the best overall performance on the seroconversion panels. Nearly all of the assays performed adequately and among them there is a great deal of choice in presentation, incubation conditions and equipment requirements. There is likely to be a kit to suit the circumstances of most laboratories involved in anti-HIV screening. One manufacturer, Labsystems, withdrew their EIA (Labsystems HIV 1+2 env Peptide EIA) from the evaluation in January 1993. The batch of kits supplied by the manufacturer for the evaluation had failed Labsystem's quality assurance in August 1992 and unused kits were recalled, although Labsystems failed to contact either Department of Health or the PHLS Hepatitis and Retrovirus Laboratory at that time. Subsequently, no evaluation data for the Labsystems HIV 1+2 env Peptide EIA is included in this report.
An Evaluation of Sixteen Combined Anti-HIV 1/2 Screening Assays by Lindsay McAlpine is 110 pages long, and a total of 27,500 words.
This makes it 37% the length of the average book. It also has 34% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 2 hours and 30 minutes to read An Evaluation of Sixteen Combined Anti-HIV 1/2 Screening Assays aloud.
An Evaluation of Sixteen Combined Anti-HIV 1/2 Screening Assays is suitable for students ages 10 and up.
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