How Long to Read Analogues of Nucleic Acid Components

By P. Roy-Burman

How Long Does it Take to Read Analogues of Nucleic Acid Components?

It takes the average reader 1 hour and 55 minutes to read Analogues of Nucleic Acid Components by P. Roy-Burman

Assuming a reading speed of 250 words per minute. Learn more

Description

The rationale for the design of structural analogues of a normal metabolite is that such compounds may interfere in the utilization or function of the metabolite. A compound which is effective in this respect may be called an antimetabolite. To be successful in chemotherapy of bacterial, viral, or tumor growth, an antimetabolite should adversely affect some vital metabolic reactions in the parasite or parasitic tissue without seriously endangering the host tissue. If a metabolic process of the offending growth is different from that of the host, it is likely that the metabolism or activity of a compound, structurally related to a metabolite involved in that process, will also be different in these cells. Such differences are useful for devising effective drugs with selective actions. Sulfanilamide, a structural analogue of para aminobenzoic acid, interferes with the utilization of this metabolite in the synthesis of folic acid, an essential factor for growth. Bacteria synthesize their own folic acid and are incapable of utilizing exogenously available folic acid. However, the situation is exactly opposite in the animal host. That is, animal tissues cannot synthesize folic acid and are absolutely dependent upon exogenous sources. These differences in metabolism make possible the use of sulfanilamide as a selective inhibitor of growth. Other antibacterial or antiparasitic drugs, such as penicillin (BURCHALL, FERONE and HITCHINGS, 1965) and inhibitors of dihydrofolate reductase (HITCHINGS and BURCHALL, 1965; HITCHINGS, 1964; BURCHALL and HITCHINGS, 1965) have analogous desirable selective toxicity effects.

How long is Analogues of Nucleic Acid Components?

Analogues of Nucleic Acid Components by P. Roy-Burman is 114 pages long, and a total of 28,956 words.

This makes it 38% the length of the average book. It also has 35% more words than the average book.

How Long Does it Take to Read Analogues of Nucleic Acid Components Aloud?

The average oral reading speed is 183 words per minute. This means it takes 2 hours and 38 minutes to read Analogues of Nucleic Acid Components aloud.

What Reading Level is Analogues of Nucleic Acid Components?

Analogues of Nucleic Acid Components is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Analogues of Nucleic Acid Components?

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