It takes the average reader 1 hour and 10 minutes to read Computational Approaches for Identifying Drugs Against Alzheimer's Disease by Radha Mahendran
Assuming a reading speed of 250 words per minute. Learn more
Alzheimer’s disease is the most common form of dementia which is incurable. Although some kinds of memory loss are normal during aging, these are not severe enough to interfere with the level of function. ß-Secretase is an important protease in the pathogenesis of Alzheimer’s disease. Some statine-based peptidomimetics show inhibitory activities to the ß-secretase. To explore the inhibitory mechanism, molecular docking and three-dimensional quantitative structure-activity relationship (3D-QSAR) studies on these analogues were performed. Quantitative structure-activity relationship (QSAR) modeling pertains to the construction of predictive models of biological activities as a function of structural and molecular information of a compound library. The concept of QSAR has typically been used for drug discovery and development and has gained wide applicability for correlating molecular information with not only biological activities but also with other physicochemical properties, which has therefore been termed quantitative structure-property relationship (QSPR). In this study, 3D QSAR and pharmacophore mapping studies were carried out using Accelrys Discovery Studio 2.1. The best nine drugs were selected from the 16 ligands and pharmacophore features were generated.
Computational Approaches for Identifying Drugs Against Alzheimer's Disease by Radha Mahendran is 68 pages long, and a total of 17,544 words.
This makes it 23% the length of the average book. It also has 21% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 1 hour and 35 minutes to read Computational Approaches for Identifying Drugs Against Alzheimer's Disease aloud.
Computational Approaches for Identifying Drugs Against Alzheimer's Disease is suitable for students ages 8 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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