How Long to Read Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia

By Andrew David Schulman

How Long Does it Take to Read Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia?

It takes the average reader and 34 minutes to read Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia by Andrew David Schulman

Assuming a reading speed of 250 words per minute. Learn more

Description

The oxidative hypothesis of schizophrenia has recently emerged as leading candidate for the pathological mechanisms of the disease. At its core, the hypothesis states that alterations within redox regulatory systems in the brain produce a cascade of dysfunction that ultimately results in schizophrenia. Here I present early results indicating that redox regulation of NMDA receptors within parvalbumin-positive inhibitory (PV+) neurons may play a central role in the development of the disorder. These experiment were performed by first mutating the gene for the NR2A subunit of NMDA receptors to lack a specific redox site, then the gene was inserted into neurons, utilizing a virus, to examine the role of redox-regulation of NMDA receptors in maintaining the inhibitory phenotype of PV+ neurons. The results from this experiment show that the removal of the redox regulatory site from the subunit attenuated the effects of an NMDA receptor antagonist, ketamine, on downregulating PV and GAD67 in PV+ neurons. These results suggest a role for redox dysregulation of NMDA receptors in the ketamine model of schizophrenia.

How long is Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia?

Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia by Andrew David Schulman is 34 pages long, and a total of 8,636 words.

This makes it 11% the length of the average book. It also has 11% more words than the average book.

How Long Does it Take to Read Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia Aloud?

The average oral reading speed is 183 words per minute. This means it takes and 47 minutes to read Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia aloud.

What Reading Level is Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia?

Redox Regulation of NMDA Receptors in a Ketamine Model of Schizophrenia is suitable for students ages 8 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

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