It takes the average reader 6 hours and 19 minutes to read Biological DNA Sensor by Sivapriya Kailasan Vanaja
Assuming a reading speed of 250 words per minute. Learn more
The innate immune response serves as the first line of defense against microbial infections by detecting pathogen-associated molecular patterns through germline-encoded pattern recognition receptors. Proteins of the PYHIN family have gained substantial research focus in recent years as central mediators of innate immune responses induced by cytosolic microbial DNA. Sensing of DNA by PYHINs typically leads to activation of inflammasomes and/or type I interferon responses that are crucial for host defense against invading pathogens. Certain members of the family are also involved in the development of autoimmune diseases as well as transcriptional regulation. Although the generation of knockout mice strains has unraveled the essential role of PYHIN proteins such as AIM2 in the development of antimicrobial innate immune responses, the exact biological role of several other PYHIN family members remains to be understood. This chapter reviews the important discoveries on PYHIN proteins and their role in microbial defense, autoimmunity and transcriptional regulation.
Biological DNA Sensor by Sivapriya Kailasan Vanaja is 368 pages long, and a total of 94,944 words.
This makes it 124% the length of the average book. It also has 116% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 8 hours and 38 minutes to read Biological DNA Sensor aloud.
Biological DNA Sensor is suitable for students ages 12 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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