How Long to Read Cell Survival Programs and Ischemia/Reperfusion

How Long Does it Take to Read Cell Survival Programs and Ischemia/Reperfusion?

It takes the average reader 2 hours and 13 minutes to read Cell Survival Programs and Ischemia/Reperfusion by Maike Krenz

Assuming a reading speed of 250 words per minute. Learn more

Description

The major purpose of this book is to review the evidence supporting the concept that intrinsic cell survival programs can be activated by a variety of mildly noxious stimuli or pharmacologic agents to confer protection against the deleterious effects of ischemia/reperfusion (I/R). We begin with a discussion of the concept of hormesis (a term used most extensively in the toxicologic literature which refers to biphasic cellular responses that depend on concentration or intensity of a stimulus), review the seminal studies that led to the discovery of the cardioprotective effects of ischemic preconditioning, and outline its therapeutic potential (Chapter 1). This is followed by a summary of our current understanding of the mechanisms of I/R injury (Chapter 2), as this provides several points of intervention in limiting postischemic tissue injury that may be targeted by the adaptive programs invoked by conditioning stimuli. Chapters 3 and 4 focus on the mechanisms underlying ischemic pre-, post-, and remote conditioning, which establishes the mechanistic rationale for development of pharmacologic conditioning strategies that may mimic the remarkably powerful effects of ischemic conditioning (and are covered in Chapter 5). Lifestyle interventions, including exercise, caloric restriction, and consumption of alcoholic beverages and/or phytochemicals, that may induce hormetic responses will also be reviewed in this chapter. While the promise for conditioning as a therapeutic approach is enormous, there are obstacles to its practical application in patients, which are covered in Chapter 6. The final chapter (Chapter 7) examines the extension of our mechanistic understanding of the signaling pathways invoked by conditioning stimuli into the realm of gene therapy and to the preservation of stem cell viability in the harsh ischemic environment as natural translational outgrowths of preconditioning into therapeutics.

How long is Cell Survival Programs and Ischemia/Reperfusion?

Cell Survival Programs and Ischemia/Reperfusion by Maike Krenz is 132 pages long, and a total of 33,264 words.

This makes it 45% the length of the average book. It also has 41% more words than the average book.

How Long Does it Take to Read Cell Survival Programs and Ischemia/Reperfusion Aloud?

The average oral reading speed is 183 words per minute. This means it takes 3 hours and 1 minute to read Cell Survival Programs and Ischemia/Reperfusion aloud.

What Reading Level is Cell Survival Programs and Ischemia/Reperfusion?

Cell Survival Programs and Ischemia/Reperfusion is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Cell Survival Programs and Ischemia/Reperfusion?

Cell Survival Programs and Ischemia/Reperfusion by Maike Krenz is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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