How Long to Read Chronic Granulomatous Disease and Neutrophil Extracellular Traps

How Long Does it Take to Read Chronic Granulomatous Disease and Neutrophil Extracellular Traps?

It takes the average reader 2 hours and 39 minutes to read Chronic Granulomatous Disease and Neutrophil Extracellular Traps by Matteo Bianchi

Assuming a reading speed of 250 words per minute. Learn more

Description

Chronic granulomatous disease (CGD) is a group of primary immunodeficiencies caused by mutations in genes encoding phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase subunits (gp91phox, p22phox, p47phox, p67phox, and p40phox). CGD phagocytes do not produce reactive oxygen species, kill microbes poorly and consequently patients are susceptible to recurrent life-threatening bacterial and fungal infections. Aspergillus spp. infections, which cause pneumonia and disseminated disease, are the leading cause of death in CGD patients. Up to now it was unclear how neutrophils control Aspergillus species in healthy individuals. We showed for the first time that the microbicidal pathway through neutrophil extracellular traps (NETs) is efficient against A. nidulans conidia and hyphae in vitro, and that restoration of NET formation was achieved by complementation of NADPH oxidase function by gene therapy in a patient with X-linked CGD. This aided clearing severe invasive A. nidulans infection in vivo. We demonstrated the critical role of NET-associate calprotectin for dose-dependent fungistatic of fungicidal anti-Aspergillus activity by Zn2+ sequestration.

How long is Chronic Granulomatous Disease and Neutrophil Extracellular Traps?

Chronic Granulomatous Disease and Neutrophil Extracellular Traps by Matteo Bianchi is 156 pages long, and a total of 39,936 words.

This makes it 53% the length of the average book. It also has 49% more words than the average book.

How Long Does it Take to Read Chronic Granulomatous Disease and Neutrophil Extracellular Traps Aloud?

The average oral reading speed is 183 words per minute. This means it takes 3 hours and 38 minutes to read Chronic Granulomatous Disease and Neutrophil Extracellular Traps aloud.

What Reading Level is Chronic Granulomatous Disease and Neutrophil Extracellular Traps?

Chronic Granulomatous Disease and Neutrophil Extracellular Traps is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Chronic Granulomatous Disease and Neutrophil Extracellular Traps?

Chronic Granulomatous Disease and Neutrophil Extracellular Traps by Matteo Bianchi is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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