It takes the average reader 6 hours and 9 minutes to read Clinical Trial Design by Guosheng Yin
Assuming a reading speed of 250 words per minute. Learn more
A balanced treatment of the theories, methodologies, and designissues involved in clinical trials using statisticalmethods There has been enormous interest and development in Bayesianadaptive designs, especially for early phases of clinical trials.However, for phase III trials, frequentist methods still play adominant role through controlling type I and type II errors in thehypothesis testing framework. From practical perspectives, ClinicalTrial Design: Bayesian and Frequentist Adaptive Methods providescomprehensive coverage of both Bayesian and frequentist approachesto all phases of clinical trial design. Before underpinning variousadaptive methods, the book establishes an overview of thefundamentals of clinical trials as well as a comparison of Bayesianand frequentist statistics. Recognizing that clinical trial design is one of the mostimportant and useful skills in the pharmaceutical industry, thisbook provides detailed discussions on a variety of statisticaldesigns, their properties, and operating characteristics for phaseI, II, and III clinical trials as well as an introduction to phaseIV trials. Many practical issues and challenges arising in clinicaltrials are addressed. Additional topics of coverage include: Risk and benefit analysis for toxicity and efficacytrade-offs Bayesian predictive probability trial monitoring Bayesian adaptive randomization Late onset toxicity and response Dose finding in drug combination trials Targeted therapy designs The author utilizes cutting-edge clinical trial designs andstatistical methods that have been employed at the world's leadingmedical centers as well as in the pharmaceutical industry. Thesoftware used throughout the book is freely available on the book'srelated website, equipping readers with the necessary tools fordesigning clinical trials. Clinical Trial Design is an excellent book for courses on thetopic at the graduate level. The book also serves as a valuablereference for statisticians and biostatisticians in thepharmaceutical industry as well as for researchers andpractitioners who design, conduct, and monitor clinical trials intheir everyday work.
Clinical Trial Design by Guosheng Yin is 364 pages long, and a total of 92,456 words.
This makes it 123% the length of the average book. It also has 113% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 8 hours and 25 minutes to read Clinical Trial Design aloud.
Clinical Trial Design is suitable for students ages 12 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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