It takes the average reader to read Computational Approaches for Drug Solubility Measurements by Dilpreet Singh
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olubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities as well as for the generic development. More than 40% NCEs (new chemical entities) developed in pharmaceutical industry are practically insoluble in water. Solubility is a major challenge for formulation scientist. Any drug to be absorbed must be present in the form of solution at the site of absorption. Various techniques are used for the enhancement of the solubility of poorly soluble drugs which include physical and chemical modifications of drug and other methods like particle size reduction, crystal engineering, salt formation, solid dispersion, use of surfactant, complexation, and so forth. Selection of solubility improving method depends on drug property, site of absorption, and required dosage form characteristics.
Computational Approaches for Drug Solubility Measurements by Dilpreet Singh is 0 pages long, and a total of 0 words.
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The average oral reading speed is 183 words per minute. This means it takes to read Computational Approaches for Drug Solubility Measurements aloud.
Computational Approaches for Drug Solubility Measurements is suitable for students ages 2 and up.
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