How Long to Read Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG.

How Long Does it Take to Read Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG.?

It takes the average reader 3 hours and 20 minutes to read Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. by Sandeep Gupta

Assuming a reading speed of 250 words per minute. Learn more

Description

Fcgamma receptors present on monocytes and macrophages clear pathogens engaged by antibodies through the process of endocytosis. Upon being clustered by immune complexes, Fcgamma receptors initiate signaling that lead to cellular activation and cytokine secretion, processes that are likely terminated upon receptor internalization and subsequent degradation. In many disease states, however, Fcgamma receptors encounter their ligands in the tissue deposited form that cannot be readily internalized. In this project, we examined kinetics of Erk 1/2 phosphorylation and TNF-alpha secretion in enriched human primary monocytes in response to stimulation of Fcgamma receptors by soluble heat aggregated IgG or plastic surface-bound IgG, to mimic immune complexes and tissue-deposited IgG, respectively. Soluble aggregated IgG induced transient and robust signaling, leading to peak levels of phospho-Erk 1/2 by 15 minutes and TNF-alpha secretion by 1 hour, in contrast to surface-bound IgG, which caused sustained signaling lasting for hours, supporting the hypothesis that signal termination is dependent upon receptor internalization.

How long is Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG.?

Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. by Sandeep Gupta is 196 pages long, and a total of 50,176 words.

This makes it 66% the length of the average book. It also has 61% more words than the average book.

How Long Does it Take to Read Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. Aloud?

The average oral reading speed is 183 words per minute. This means it takes 4 hours and 34 minutes to read Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. aloud.

What Reading Level is Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG.?

Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG.?

Fcgamma Receptor Signaling in Response to Soluble Versus Immobilized IgG. by Sandeep Gupta is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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