How Long to Read Genetic Steroid Disorders

By Berenice B. Mendonca

How Long Does it Take to Read Genetic Steroid Disorders?

It takes the average reader 6 hours and 55 minutes to read Genetic Steroid Disorders by Berenice B. Mendonca

Assuming a reading speed of 250 words per minute. Learn more

Description

17β-hydroxysteroid dehydrogenase 3 deficiency (17β-HSD3) consists of a defect in the last phase of steroidogenesis, in which androstenedione is converted into testosterone and estrone into estradiol. Patients present female-like or with ambiguous genitalia at birth and most affected males are raised as females. Virilization in subjects with 17β-HSD3 deficiency occurs at the time of puberty and almost half change to be males. Maintenance of the testes in patients raised male is safe and recommended, except when the testes cannot be positioned inside the scrotum. The phenotype of 46,XY disorders of sex development (DSD) owing to 17β-HSD3 deficiency is extremely variable and is clinically indistinguishable from other causes of 46,XY DSD such as partial androgen insensitivity syndrome and 5α-reductase 2 deficiency. Laboratory diagnosis is based on elevated serum levels of androstenedione and estrone and low levels of testosterone and estradiol, resulting in elevated androstenedione:testosterone and estrone:estradiol ratios, indicating an impairment of the conversion of 17-keto into 17-hydroxysteroids. The disorder is due to homozygous or compound heterozygous mutations in the HSD17B3 gene that encodes the 17β-HSD3 isoenzyme. Molecular genetic testing confirms the diagnosis and provides the orientation for genetic counseling. Our proposal in this article is to review the reported and our own cases of 17β-HSD3 deficiency.

How long is Genetic Steroid Disorders?

Genetic Steroid Disorders by Berenice B. Mendonca is 406 pages long, and a total of 103,936 words.

This makes it 137% the length of the average book. It also has 127% more words than the average book.

How Long Does it Take to Read Genetic Steroid Disorders Aloud?

The average oral reading speed is 183 words per minute. This means it takes 9 hours and 27 minutes to read Genetic Steroid Disorders aloud.

What Reading Level is Genetic Steroid Disorders?

Genetic Steroid Disorders is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Genetic Steroid Disorders?

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