How Long to Read How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease

How Long Does it Take to Read How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease?

It takes the average reader 3 hours and 29 minutes to read How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease by Rohit Kumar

Assuming a reading speed of 250 words per minute. Learn more

Description

Doctoral Thesis / Dissertation from the year 2021 in the subject Biology - Neurobiology, grade: N/A, Technical University of Munich (German Center for Neurodegenerative Diseases (DZNE)), language: English, abstract: Lewy body (LB) disorders, such as dementia with LBs and Parkinson’s disease with dementia (PDD) are characterized by their pathological hallmark, i.e., the gradual appearance of LBs. Therefore, a deep understanding of the molecular and cellular mechanism, favoring the formation of LBs is required.These proteinaceous inclusions are found in different cell types of the nervous system. The key constituent protein-component of such inclusions is the protein alpha-synuclein (α-Syn). α-Syn along with other bio-active material gets secreted as content of extracellular vesicles (EVs). These vesicles not only excrete bioactive material but are also able to transport it to distant sites, and therefore have implications for disease pathology seeding and spreading.Using patch-clamp electrophysiology techniques along with simultaneous real-time molecular imaging, we determined the kinetics of EV-release in hippocampal neurons. We designed a pH-sensitive molecular tag, targeted specifically to membranes of EVs and applied this method to study stimulus-responsive MVB-PM fusion, in order to determine the kinetics, specific stimuli and regulators of such events. In addition, we analyzed the EV-content by performing mass spectrometry (MS) analysis and identifyed LBP-related molecular interactions.

How long is How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease?

How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease by Rohit Kumar is 205 pages long, and a total of 52,275 words.

This makes it 69% the length of the average book. It also has 64% more words than the average book.

How Long Does it Take to Read How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease Aloud?

The average oral reading speed is 183 words per minute. This means it takes 4 hours and 45 minutes to read How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease aloud.

What Reading Level is How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease?

How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease?

How Stimulus-responsive Extracellular Vesicle Release is Regulated and Associated to Lewy body disease by Rohit Kumar is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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