It takes the average reader 1 hour and 17 minutes to read Identifying Novel Inborn Errors of the Immune System by Elisabeth Salzer
Assuming a reading speed of 250 words per minute. Learn more
In her study Elisabeth Salzer describes three novel monogenic diseases. For CD27 deficiency Elisabeth Salzer describes a large cohort of patients. Although all patients shared the same causative missense mutation, they displayed diverse clinical presentations. In another patient she was able to identify a mutation in PRKCD resulting in a primary immunodeficiency with severe Lupus-like autoimmunity. The patient exhibited increased mRNA levels of IL6. Therefore, treatment with Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody was suggested. In a family with a history of deaths due to inflammatory bowel disease she identified a missense mutation in IL21. She produced wild type and mutated IL-21 protein and demonstrated a loss of function phenotype. As IL-21 is in clinical trials, she proposed a potentially curative treatment option. These discoveries contributed to the understanding of the multifaceted regulatory mechanisms of the immune system and highlighted essential players in these complex signaling networks.
Identifying Novel Inborn Errors of the Immune System by Elisabeth Salzer is 76 pages long, and a total of 19,456 words.
This makes it 26% the length of the average book. It also has 24% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 1 hour and 46 minutes to read Identifying Novel Inborn Errors of the Immune System aloud.
Identifying Novel Inborn Errors of the Immune System is suitable for students ages 8 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
When deciding what to show young students always use your best judgement and consult a professional.
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