How Long to Read Identifying Pharmacological Therapeutics for Aggressive Fibromatosis

How Long Does it Take to Read Identifying Pharmacological Therapeutics for Aggressive Fibromatosis?

It takes the average reader 3 hours and 33 minutes to read Identifying Pharmacological Therapeutics for Aggressive Fibromatosis by Helen Hong

Assuming a reading speed of 250 words per minute. Learn more

Description

Aggressive fibromatosis is a fibroproliferative tumour that can occur as a sporadic lesion or a manifestation in FAP patients. Tumours are characterized by the stabilization of beta-catenin. Current therapies have yet to offer complete success for primary and recurrent tumours, and there remains a need for more effective therapeutic strategies. In this work, we demonstrate the anti-neoplastic and beta-catenin modulating capacities of Nefopam, a currently approved analgesic agent. We found that Nefopam was able to decrease cell viability and proliferation as well as total beta-catenin levels in human aggressive fibromatosis tumour cells in vitro. Furthermore, Nefopam reduced the number of tumours formed in the Apc+/Apc 1638N aggressive fibromatosis mouse model. We also demonstrated that androgens contribute to the development of tumours and could also modulate beta-catenin levels as indicated in Testosterone-treated orchidectomized Apc +/Apc1638N mice. Together, this work suggests that Nefopam and androgen signaling-blocking agents are potential candidates to effectively manage aggressive fibromatosis.

How long is Identifying Pharmacological Therapeutics for Aggressive Fibromatosis?

Identifying Pharmacological Therapeutics for Aggressive Fibromatosis by Helen Hong is 212 pages long, and a total of 53,424 words.

This makes it 72% the length of the average book. It also has 65% more words than the average book.

How Long Does it Take to Read Identifying Pharmacological Therapeutics for Aggressive Fibromatosis Aloud?

The average oral reading speed is 183 words per minute. This means it takes 4 hours and 51 minutes to read Identifying Pharmacological Therapeutics for Aggressive Fibromatosis aloud.

What Reading Level is Identifying Pharmacological Therapeutics for Aggressive Fibromatosis?

Identifying Pharmacological Therapeutics for Aggressive Fibromatosis is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Identifying Pharmacological Therapeutics for Aggressive Fibromatosis?

Identifying Pharmacological Therapeutics for Aggressive Fibromatosis by Helen Hong is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

To buy Identifying Pharmacological Therapeutics for Aggressive Fibromatosis by Helen Hong on Amazon click the button below.