How Long to Read Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure

By Jed Alexander Bassein

How Long Does it Take to Read Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure?

It takes the average reader to read Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure by Jed Alexander Bassein

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Description

Studies have shown that early-life is a critical developmental period for the respiratory and immune systems. Wildfires and tobacco smoke are two exposure dynamics that occur frequently in neonatal populations. Climate change and increased population density at the urban-wildland interface increase the potential for exposure to wildfire smoke, while tobacco smoke exposure is a leading cause of morbidity in infant populations. Wildfire and tobacco are generated through the combustion of biomass; however, wildfires that occur in urban dwellings can generate more toxic particulate matter. In contrast, tobacco smoke has the added toxicity of nicotine, which is harmful to developing children. In this study, we characterized the persistent cardiopulmonary and immune-associated effects in female non-human primate rhesus monkeys that were exposed to wildfire smoke during early-life. During adulthood, we found evidence of reduced lung volumes and pulmonary remodeling, which suggested pulmonary fibrosis might be occurring. We also observed dysregulation of the myeloid-associated immune response, changes in humoral immunity, and cellular immunity. We describe a novel population of T helper cells that are referred to as Th31 cells. Th31 cells are phenotypically defined as being CD3+CD4+CD31+MHCII+CD2− and capable of producing IL-6, IL-8, and IL-22 after stimulation. To investigate the effect of early-life exposure to environmental tobacco smoke (ETS) on myeloid-derived stem cell differentiation we developed an in vitro bone marrow-derived dendritic cell (BMDC) culture schematic as well as an adoptive bone marrow transplant (BMT) model.

How long is Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure?

Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure by Jed Alexander Bassein is 0 pages long, and a total of 0 words.

This makes it 0% the length of the average book. It also has 0% more words than the average book.

How Long Does it Take to Read Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure Aloud?

The average oral reading speed is 183 words per minute. This means it takes to read Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure aloud.

What Reading Level is Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure?

Immune and Pulmonary Dysregulation Following Early-life Smoke Exposure is suitable for students ages 2 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

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