How Long to Read Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery

By Yao Peng

How Long Does it Take to Read Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery?

It takes the average reader and 57 minutes to read Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery by Yao Peng

Assuming a reading speed of 250 words per minute. Learn more

Description

Recently, there has been remarkable interest in mining the chemical diversity in specialized metabolites scaffolds to identify novel molecules with altered bioactivity from natural source. Here, we present the use of MS/MS networking guided comparative metabolomics to profile sequenced and unsequenced bacteria. This enables the dereplication of known specialized metabolites as well as the discovery of new analogs that are produced in an environmental unsequenced bacterium Streptomyces sp. DSM5940 by comparing the metabolic output with a sequenced bacterium Streptomyces roseosporus. The following differential comparison of gene cluster profiling, MS/MS and 2D NMR greatly accelerates the structure elucidation process, allowing us to rapidly identify an analog of the stenothricins in which a lysine is changed to a serine, which we have named stenothrisercin. The finally cytological profiling indicates lysine may be an essential structural motif for the antimicrobial activity. Our study demonstrates MS/MS networking, along with differential comparison significantly accelerates the process of mining new natural product analogs.

How long is Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery?

Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery by Yao Peng is 56 pages long, and a total of 14,336 words.

This makes it 19% the length of the average book. It also has 18% more words than the average book.

How Long Does it Take to Read Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery Aloud?

The average oral reading speed is 183 words per minute. This means it takes 1 hour and 18 minutes to read Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery aloud.

What Reading Level is Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery?

Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery is suitable for students ages 8 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Mass Spectrometry Guided Analogs of Bioactive Molecule Discovery?

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