How Long to Read Model-Assisted Bayesian Designs for Dose Finding and Optimization

How Long Does it Take to Read Model-Assisted Bayesian Designs for Dose Finding and Optimization?

It takes the average reader 4 hours and 7 minutes to read Model-Assisted Bayesian Designs for Dose Finding and Optimization by Ying Yuan

Assuming a reading speed of 250 words per minute. Learn more

Description

Bayesian adaptive designs provide a critical approach to improve the efficiency and success of drug development that has been embraced by the US Food and Drug Administration (FDA). This is particularly important for early phase trials as they form the basis for the development and success of subsequent phase II and III trials. The objective of this book is to describe the state-of-the-art model-assisted designs to facilitate and accelerate the use of novel adaptive designs for early phase clinical trials. Model-assisted designs possess avant-garde features where superiority meets simplicity. Model-assisted designs enjoy exceptional performance comparable to more complicated model-based adaptive designs, yet their decision rules often can be pre-tabulated and included in the protocol—making implementation as simple as conventional algorithm-based designs. An example is the Bayesian optimal interval (BOIN) design, the first dose-finding design to receive the fit-for-purpose designation from the FDA. This designation underscores the regulatory agency's support of the use of the novel adaptive design to improve drug development. Features Represents the first book to provide comprehensive coverage of model-assisted designs for various types of dose-finding and optimization clinical trials Describes the up-to-date theory and practice for model-assisted designs Presents many practical challenges, issues, and solutions arising from early-phase clinical trials Illustrates with many real trial applications Offers numerous tips and guidance on designing dose finding and optimization trials Provides step-by-step illustrations of using software to design trials Develops a companion website (www.trialdesign.org) to provide freely available, easy-to-use software to assist learning and implementing model-assisted designs Written by internationally recognized research leaders who pioneered model-assisted designs from the University of Texas MD Anderson Cancer Center, this book shows how model-assisted designs can greatly improve the efficiency and simplify the design, conduct, and optimization of early-phase dose-finding trials. It should therefore be a very useful practical reference for biostatisticians, clinicians working in clinical trials, and drug regulatory professionals, as well as graduate students of biostatistics. Novel model-assisted designs showcase the new KISS principle: Keep it simple and smart!

How long is Model-Assisted Bayesian Designs for Dose Finding and Optimization?

Model-Assisted Bayesian Designs for Dose Finding and Optimization by Ying Yuan is 239 pages long, and a total of 61,901 words.

This makes it 81% the length of the average book. It also has 76% more words than the average book.

How Long Does it Take to Read Model-Assisted Bayesian Designs for Dose Finding and Optimization Aloud?

The average oral reading speed is 183 words per minute. This means it takes 5 hours and 38 minutes to read Model-Assisted Bayesian Designs for Dose Finding and Optimization aloud.

What Reading Level is Model-Assisted Bayesian Designs for Dose Finding and Optimization?

Model-Assisted Bayesian Designs for Dose Finding and Optimization is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Model-Assisted Bayesian Designs for Dose Finding and Optimization?

Model-Assisted Bayesian Designs for Dose Finding and Optimization by Ying Yuan is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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