How Long to Read Pediatric Neurology Part III

By Phillip L. Pearl

How Long Does it Take to Read Pediatric Neurology Part III?

It takes the average reader 12 hours and 17 minutes to read Pediatric Neurology Part III by Phillip L. Pearl

Assuming a reading speed of 250 words per minute. Learn more

Description

Pediatric neurotransmitter disorders refer to a constellation of inherited neurometabolic syndromes attributable to disturbances of neurotransmitter synthesis, degradation, or transport. Monoamine deficiencies represent defects in synthesis of dopamine, serotonin, norepinephrine, and epinephrine or in availability of tetrahydrobiopterin, an important cofactor for monoamine synthesis. Some disorders do not manifest peripheral hyperphenyalaninemia and require CSF neurotransmitter metabolite assay for diagnosis. These include Segawa dopa-responsive dystonia and enzymatic deficiencies of aromatic amino acid decarboxylase, tyrosine hydroxylase, and sepiapterin reductase. The first, autosomal dominantly inherited GTP cyclohydrolase deficiency, has a satisfying response to therapy at any age with benefits maintained over time. The others have more severe and treatment-refractory phenotypes, typically with manifestations well beyond movement disorders. Disorders detectable by elevated serum phenylalanine are deficiencies of GTP cyclohydrolase (homozygous), pterin-carbinolamine dehydratase, dihydropteridine reductase, and pyruvoyl-tetrahydropterin synthase. The latter is the most prevalent and heterogeneous but typically has infantile onset with extrapyramidal as well as bulbar, hypothalamic, limbic, and epileptic manifestations. There are therapeutic roles for neurotransmitter supplementation, and dopaminergic agonists. Basal ganglia calcifications in dihydropteridine reductase deficiency are reversible with folinic acid. Deficiencies of monoamine degradation lead to cognitive, behavioral, and autonomic disorders.

How long is Pediatric Neurology Part III?

Pediatric Neurology Part III by Phillip L. Pearl is 732 pages long, and a total of 184,464 words.

This makes it 247% the length of the average book. It also has 225% more words than the average book.

How Long Does it Take to Read Pediatric Neurology Part III Aloud?

The average oral reading speed is 183 words per minute. This means it takes 16 hours and 48 minutes to read Pediatric Neurology Part III aloud.

What Reading Level is Pediatric Neurology Part III?

Pediatric Neurology Part III is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Pediatric Neurology Part III?

Pediatric Neurology Part III by Phillip L. Pearl is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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