How Long to Read PI3K signalling

By Klaus Okkenhaug

How Long Does it Take to Read PI3K signalling?

It takes the average reader 2 hours and 20 minutes to read PI3K signalling by Klaus Okkenhaug

Assuming a reading speed of 250 words per minute. Learn more

Description

The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the role of this pathway in cells of the immune system has been made in recent years, starting with analysis of various PI3K and Pten knockout mice and subsequently mTOR and Foxo knockout mice. Together, these experiments have revealed how PI3Ks control B cell and T cell development, T helper cell differentiation, regulatory T cell development and function, B cell and T cell trafficking, immunoglobulin class switching and much, much more. The PI3Kd inhibitor idelalisib has recently been approved for the treatment of B cell lymphoma. Clinical trials of other PI3K inhibitors in autoimmune and inflammatory diseases are also in progress. This is an opportune time to consider a Research Topic considering when what we have learned about the PI3K signalling module in lymphocyte biology and how this is making an impact on clinical immunology and haematology.

How long is PI3K signalling?

PI3K signalling by Klaus Okkenhaug is 140 pages long, and a total of 35,000 words.

This makes it 47% the length of the average book. It also has 43% more words than the average book.

How Long Does it Take to Read PI3K signalling Aloud?

The average oral reading speed is 183 words per minute. This means it takes 3 hours and 11 minutes to read PI3K signalling aloud.

What Reading Level is PI3K signalling?

PI3K signalling is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy PI3K signalling?

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