How Long to Read Plasticity of primary afferent neurons and sensory processing after spinal cord injury

By Alexander Rabchevsky

How Long Does it Take to Read Plasticity of primary afferent neurons and sensory processing after spinal cord injury?

It takes the average reader 3 hours and 43 minutes to read Plasticity of primary afferent neurons and sensory processing after spinal cord injury by Alexander Rabchevsky

Assuming a reading speed of 250 words per minute. Learn more

Description

Traumatic injury of the spinal cord affects the entire organism directly and indirectly. Primary injury destroys neurons and severs axons which participate in neural circuits. Secondary injuries and pathologies arise from numerous sources including systemic inflammation, consequential damage of cutaneous, muscular, and visceral tissues, and dysregulation of autonomic, endocrine and sensory- motor functions. Evidence is mounting that spinal cord injury (SCI) affects regions of the nervous system spatially remote from the injury site, as well as peripheral tissues, and alters some basic characteristics of primary afferent cell biology and physiology (cell number, size/frequency, electrophysiology, other). The degree of afferent input and processing above the lesion is generally intact, while that in the peri-lesion area is highly variable, though pathologies emerge in both regions, including a variety of pain syndromes. Primary afferent input to spinal regions below the injury and the processing of this information becomes even more important in the face of complete or partial loss of descending input because such spared sensory processing can lead to both adaptive and pathological outcomes. This issue hosts review and research articles considering mechanisms of plasticity of primary afferent neurons and sensory processing after SCI, and how such plasticity contributes to sparing and/or recovery of functions, as well as exacerbation of existing and/or emergent pathologies. A critical issue for the majority of the SCI community is chronic above-, peri-, and below-level neuropathic pain, much of which may arise, at least in part, from plasticity of afferent fibers and nociceptive circuitry. For example, autonomic dysreflexia is common hypertensive syndrome that often develops after SCI that is highly reliant on maladaptive nociceptive sensory input and processing below the lesion. Moreover, the loss of descending input leaves the reflexive components of bladder/bowel/sexual function uncoordinated and susceptible to a variety of effects through afferent fiber plasticity. Finally, proper afferent feedback is vital for the effectiveness of activity-dependent rehabilitative therapies, but aberrant nociceptive input may interfere with these approaches since they are often unchecked due to loss of descending modulation.

How long is Plasticity of primary afferent neurons and sensory processing after spinal cord injury?

Plasticity of primary afferent neurons and sensory processing after spinal cord injury by Alexander Rabchevsky is 222 pages long, and a total of 55,944 words.

This makes it 75% the length of the average book. It also has 68% more words than the average book.

How Long Does it Take to Read Plasticity of primary afferent neurons and sensory processing after spinal cord injury Aloud?

The average oral reading speed is 183 words per minute. This means it takes 5 hours and 5 minutes to read Plasticity of primary afferent neurons and sensory processing after spinal cord injury aloud.

What Reading Level is Plasticity of primary afferent neurons and sensory processing after spinal cord injury?

Plasticity of primary afferent neurons and sensory processing after spinal cord injury is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

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