How Long to Read Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases

How Long Does it Take to Read Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases?

It takes the average reader 1 hour and 45 minutes to read Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases by Takuya Hidaka

Assuming a reading speed of 250 words per minute. Learn more

Description

This book describes the author’s work on the development of sequence-specific DNA binders for the therapy of mitochondrial diseases. In the first chapter, the author provides a detailed background of pyrrole–imidazole polyamides (PIPs) and mitochondrial disease research followed by chapters presenting the author's own research and discoveries. Firstly, the developed compounds called MITO-PIPs, which recognize specific sequences in mitochondrial DNA, are presented. The following chapter demonstrates how, by introducing a DNA alkylating reagent into a MITO-PIP that recognizes the adjacent sequence to a target mutation, the copy number of mutated mitochondrial DNA was successfully reduced in live cells. Furthermore, because nuclear DNA is another important target for treating mitochondrial diseases, the author demonstrated that tri-arginine vectors can enhance nuclear uptake of PIPs and improve their biological activity in cells. This work will attract readers’ interest because it paves the way for a transgene-free chemical gene therapy for mitochondrial diseases. The book includes a detailed description of experimental procedures, especially compound synthesis. This description helps readers to have a clear image of the author’s studies and to perform similar and extended studies themselves.

How long is Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases?

Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases by Takuya Hidaka is 104 pages long, and a total of 26,416 words.

This makes it 35% the length of the average book. It also has 32% more words than the average book.

How Long Does it Take to Read Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases Aloud?

The average oral reading speed is 183 words per minute. This means it takes 2 hours and 24 minutes to read Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases aloud.

What Reading Level is Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases?

Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases?

Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases by Takuya Hidaka is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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