It takes the average reader 8 hours and 32 minutes to read Studies in Natural Products Chemistry by Pulok K. Mukherjee
Assuming a reading speed of 250 words per minute. Learn more
Matrix metalloproteinase (MMPs) are a family of zinc and calcium dependent endopeptidases. All MMPs have two molecular appearances, one is pre-peptide sequence that directs their secretion in the extracellular environment and another is pro-peptide domain that maintains them in their zymogenic form. MMPs play crucial roles in numerous pathophysiological conditions, including cancer, cardiovascular disease, autoimmune diseases, skin aging, inflammation, etc. Modulating MMP activities at transcription levels, proteolytic activation of the zymogen form, and inhibition of the active enzyme may however be useful therapeutic approaches. Although several synthetic MMP inhibitors have been identified as cytostatic, antiangiogenic, antiaging, and antiwrinkle agents and also subjected to preclinical trials, but there are consistent number of disappointments and adverse reactions. Currently, researchers are paying great deal of attention on identifying new molecular entities from nutraceuticals which includes genistein, myricetin, curcumin, xanthorhizzol, theaflavin, resveratrol, matlystatin B, nicotinamide, betulinic acid, oleanolic acid, glycyrrhetinic acid, catechin derivatives, etc. to target specific MMPs. Importance of these phytomolecules remains largely underexploited, despite increasing evidences showing their ability to act synergistically to control MMPs. This chapter highlights the recent information and investigations on natural MMP inhibitors as novel therapeutic intervention.
Studies in Natural Products Chemistry by Pulok K. Mukherjee is 504 pages long, and a total of 128,016 words.
This makes it 170% the length of the average book. It also has 156% more words than the average book.
The average oral reading speed is 183 words per minute. This means it takes 11 hours and 39 minutes to read Studies in Natural Products Chemistry aloud.
Studies in Natural Products Chemistry is suitable for students ages 12 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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