How Long to Read Towards an Understanding of Inflammation in Macrophages

How Long Does it Take to Read Towards an Understanding of Inflammation in Macrophages?

It takes the average reader 2 hours and 22 minutes to read Towards an Understanding of Inflammation in Macrophages by Dawn Xiaobin Zhang

Assuming a reading speed of 250 words per minute. Learn more

Description

This dissertation utilizes in vivo and genome-wide approaches to investigate the roles of NCoR, Rev-Erb, and Coro2A in regulating transcription in a signal-dependent manner. Chapter 1 will review our current understanding of transcriptional regulation in mammalian cells, especially how certain cell-specific enhancers and genes are selected for transcription. Chapter 2 will characterize the new and unexpected role of Rev-Erbs in regulating signal-dependent enhancers during wound healing. Unexpectedly, we found that loss of Rev-Erbs in hematopoietic cells results in accelerated wound healing. Our studies suggest that Rev-Erbs regulate a broad range of enhancers vital for wound healing and that these enhancers are neither pro-inflammatory nor anti-inflammatory. Instead, the ability of Rev-Erbs to select for a subset of "wound healing" enhancers results in the fine-tuning of macrophage-mediated responses to damaged tissue. Chapter 3 describes the generation and analysis of a Coro2A total knock-out mouse. In this chapter, we utilize a genome-wide approach to investigate the role of Coro2A, a novel member of the NCoR complex, in mediating transcriptional regulation. Furthermore, our studies show that Coro2A and NCoR cooperate to regulate the expression of lipid biosynthetic and immune response genes. Finally, Chapter 4 will discuss the broader implications of this research as a whole.

How long is Towards an Understanding of Inflammation in Macrophages?

Towards an Understanding of Inflammation in Macrophages by Dawn Xiaobin Zhang is 138 pages long, and a total of 35,604 words.

This makes it 47% the length of the average book. It also has 44% more words than the average book.

How Long Does it Take to Read Towards an Understanding of Inflammation in Macrophages Aloud?

The average oral reading speed is 183 words per minute. This means it takes 3 hours and 14 minutes to read Towards an Understanding of Inflammation in Macrophages aloud.

What Reading Level is Towards an Understanding of Inflammation in Macrophages?

Towards an Understanding of Inflammation in Macrophages is suitable for students ages 10 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

When deciding what to show young students always use your best judgement and consult a professional.

Where Can I Buy Towards an Understanding of Inflammation in Macrophages?

Towards an Understanding of Inflammation in Macrophages by Dawn Xiaobin Zhang is sold by several retailers and bookshops. However, Read Time works with Amazon to provide an easier way to purchase books.

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