How Long to Read Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform]

By Toni Davidson

How Long Does it Take to Read Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform]?

It takes the average reader 4 hours and 22 minutes to read Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform] by Toni Davidson

Assuming a reading speed of 250 words per minute. Learn more

Description

Molecular chaperones are proteins that assist in folding, refolding, disaggregation, or degradation of other proteins in the cell. This thesis includes studies of two bacterial chaperones, GroEL, which mediates protein folding, and ClpX, which mediates protein unfolding and directs proteins for degradation by ClpP. GroEL has previously been implicated in the refolding of the multisubunit bacterial RNA polymerase (RNAP). I found that GroEL was not essential for the refolding of the alpha and o subunits of RNAP. Previous studies have indicated that the N-terminal Zinc Binding Domain (ZBD) of ClpX is involved in substrate recognition. Using degradation assays and competition studies, I found that the ZBD of ClpX is important for recognizing a certain set of substrates. Placement of an N-terminal tag on ClpX results in cleavage of that tag in the presence of ClpP and ATP. This suggests that a conformational change takes place in ClpX involving the ZBD.

How long is Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform]?

Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform] by Toni Davidson is 256 pages long, and a total of 65,536 words.

This makes it 86% the length of the average book. It also has 80% more words than the average book.

How Long Does it Take to Read Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform] Aloud?

The average oral reading speed is 183 words per minute. This means it takes 5 hours and 58 minutes to read Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform] aloud.

What Reading Level is Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform]?

Towards Understanding the Functions of the GroEL and ClpX Chaperone Systems in Escherichia Coli [microform] is suitable for students ages 12 and up.

Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.

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