How Long to Read Transcriptional Regulation and Its Misregulation in Human Diseases

How Long Does it Take to Read Transcriptional Regulation and Its Misregulation in Human Diseases?

It takes the average reader to read Transcriptional Regulation and Its Misregulation in Human Diseases by Amelia Casamassimi

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Description

Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extracellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity. This control involves multiple temporal and functional steps as well as innumerable molecules including transcription factors, cofactors, and chromatin regulators. It is well known that many human disorders are characterized by global transcriptional dysregulation because most of the signaling pathways ultimately target transcription machinery. Indeed, many syndromes and genetic and complex diseases--cancer, autoimmunity, neurological and developmental disorders, and metabolic and cardiovascular diseases--can be caused by mutations/alterations in regulatory sequences, transcription factors, splicing regulators, cofactors, chromatin regulators, ncRNAs, and other components of transcription apparatus. It is worth noting that advances in our understanding of molecules and mechanisms involved in the transcriptional circuitry and apparatus lead to new insights into the pathogenetic mechanisms of various human diseases and disorders. Thus, this Special Issue is focused on molecular genetics and genomics studies exploring the effects of transcriptional misregulation on human diseases.

How long is Transcriptional Regulation and Its Misregulation in Human Diseases?

Transcriptional Regulation and Its Misregulation in Human Diseases by Amelia Casamassimi is 0 pages long, and a total of 0 words.

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The average oral reading speed is 183 words per minute. This means it takes to read Transcriptional Regulation and Its Misregulation in Human Diseases aloud.

What Reading Level is Transcriptional Regulation and Its Misregulation in Human Diseases?

Transcriptional Regulation and Its Misregulation in Human Diseases is suitable for students ages 2 and up.

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