How Long to Read Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy
By Anh Thi Ngoc Nguyen
How Long Does it Take to Read Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy?
It takes the average reader 4 hours and 57 minutes to read Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy by Anh Thi Ngoc Nguyen
Assuming a reading speed of 250 words per minute. Learn more
Description
Hypothermia therapy (HT) is used clinically following global cerebral ischemia (GCI) but its therapeutic mechanisms are not completely understood. An elucidation of such mechanisms may lead to novel therapeutic approaches that improve patient outcome. Using a murine model of GCI, we determined the effect of HT on the expression of inflammatory proteins in the hippocampus and serum. We also examined its effect on microglia/macrophage activation and neurodegeneration in the brain at 72 hours following ischemia, and its effect on long-term spatial memory/learning and contextual fear response. GCI led to increased neurodegeneration and microglia/macrophage activation in the hippocampus, and increased IL-1beta and KC protein expression in the hippocampus at 72 hours. Hypothermia therapy attenuated these inflammatory responses. It also improved spatial learning/memory at 7 and 21 days, and preserved contextual fear response 21 days post-ischemia. Hypothermia therapy attenuated the post-ischemic inflammatory response, protected hippocampal neurons, and preserved long-term memory and learning.
How long is Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy?
Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy by Anh Thi Ngoc Nguyen is 288 pages long, and a total of 74,304 words.
This makes it 97% the length of the average book. It also has 91% more words than the average book.
How Long Does it Take to Read Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy Aloud?
The average oral reading speed is 183 words per minute. This means it takes 6 hours and 46 minutes to read Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy aloud.
What Reading Level is Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy?
Molecular Mechanisms Of Neuroinflammation Following Global Cerebral Ischemia: The Role Of Hypothermia Therapy is suitable for students ages 12 and up.
Note that there may be other factors that effect this rating besides length that are not factored in on this page. This may include things like complex language or sensitive topics not suitable for students of certain ages.
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